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Research Scientist: Biology
Biohaven Pharmaceuticals Inc
| Position Summary: Biohaven is seeking a highly skilled and technically proficient Research Scientist to join our Ion Channel Pharmacology team in a contract role. This scientist will play a critical role in the design, execution, and analysis of in vitro and ex vivo assays aimed at characterizing ion channel modulators. The role requires deep hands-on experience with cell-based assay technologies, supporting ion channel-focused drug discovery programs. Key Responsibilities: · Perform routine mammalian tissue culture (cell lines and neuronal cultures), including neuronal differentiation and maintenance of iPSC-derived neuronal models. · Harvest rodent tissues, dissect specific brain regions, and prepare samples for downstream applications. · Design and execute manual patch-clamp, automated patch-clamp (APC), and/or multi-electrode array (MEA) experiments to evaluate ion channel modulators in recombinant cell lines, primary neurons, and iPSC-derived neurons. · Analyze, interpret, and present experimental data in internal team meetings and contribute to technical reports and data packages. · Maintain meticulous lab records, adhere to SOPs and lab safety regulation guidelines, and ensure high data integrity and reproducibility.
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Required Qualifications: · BS/MS in Neuroscience, Pharmacology, Physiology, Cell Biology, or a related field. · Minimum 3 years of hands-on experience in vitro pharmacology in academic, biotech, or pharmaceutical settings. · Strong background in mammalian cell culture including primary and iPSC-derived neurons. · Experience with tissue harvesting, brain region dissection, and processing of neural tissue. · Experience in manual patch-clamp electrophysiology, automated patch-clamp electrophysiology (APC), multielectrode array (MEA), or ELISA techniques is strongly preferred. Key Attributes: · Detail-oriented in experimental execution, with strong problem-solving skills and scientific curiosity. · Effective communicator, both written and verbal. · Team-oriented with the ability to work in a fast-paced, interdisciplinary environment. · High personal integrity and self-motivation with a strong sense of accountability. This is an excellent opportunity to contribute to impactful ion channel drug discovery efforts in a dynamic and collaborative research environment. |
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